This edible shellfish has been a major part of the diet of the local population of New Zealand. In 1974 an American research program studying marine molluscs for anti-cancer properties found GLM to be a potentially natural remedy for arthritis. It naturally contained the components the body required to effectively give relief from the symptoms of arthritis without the adverse side effects associated with drug therapies and pain killers.

There have been no reports of any contra-indications when GLME has been taken together with other anti-inflammatory products whether these have been drugs or natural preparations. It is unlikely that GLME would contra-indicate with other pharmaceuticals due to its basic food status. However, it would be preferable for it not to be used if a person was using monoamine oxidase inhibitory drugs (anti-depressants which are now not generally used). Also, it is important to note that GLME should not be used to treat gouty arthritis. The reason for this is that gout is caused by an excess of uric acid which precipitates in the joints. In common with cheese and wine, shellfish contain a significant level of purine nitrogen which would act as a precursor for the biosynthesis of uric acid!

Since its discovery in 1974, Green Lipped Mussel Extract (GLME) has now been subjected to more than forty years of quality scientific research and proven in laboratory and clinical trials, to be effective in relieving the symptoms of both rheumatoid and osteo forms of arthritis.  GLME manufactured by Healtheries of New Zealand is now available in India through their Authorised representatives – Perma Healthcare. The cost for this therapy of 1000mg/day comes to Rs 50/- per day for first three months, which can be later reduced to 500 mg/day, i.e. Rs 25/- per day.