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Shareholder FAQ2019-02-27T12:11:27+05:30
Defends Against Pollution2021-09-24T12:59:35+05:30

Children are more vulnerable to the adverse effects of air pollution than are adults. Children have increased exposure to many air pollutants compared with adults because children spend more time outdoors than adults, thus they have increased exposure to outdoor air pollution.

There are numerous toxins floating in the air we breathe, which are regularly being produced by motor vehicles, industrial facilities, residential wood combustion, agricultural burning, and many other sources. The levels tend to be highest on warm, sunny, windless days and often peak in mid-afternoon when children are most likely to be playing outside.

Effects of Pollution on the Skin of children:

  • Ozone in photochemical smog diminishes Vitamin E levels in the skin, disturbing wound-healing processes and stimulating oxidative stress.
  • Skin exposed to pollution suffers a higher sebum secretion rate as compared to non-polluted areas.
  • Cutaneous pH tends to reduce when exposed to pollution.
  • Squalene and vitamin E are the main antioxidants at the skin surface. Squalene is reduced in polluted areas because it is mobilized to fight oxidative stress in the skin.

Human skin faces an aerial oxidative environment naturally. The environment presents an unpredictable oxidative potential because it is enhanced by solar rays probably combined with aerial-borne pollutants which most commonly act as catalysts in the diverse oxidative pathways. The human sebum highly present on the upper parts of the body as the face is thus a natural “receptor” of these oxidative actions. 10–20 % of sebum is Squalene which is highly sensitive towards different types of Reactive Oxygen Species. Squalene appears as natural bio-markers of most oxidative reactions on the cutaneous tissue.

Squalene being an antioxidant can act as oxygen supplement. It is highly sensitive to singlet oxygen which is a very reactive oxidative species. It assists the oxygen delivery throughout the body. The antioxidants neutralize free radicals. Increased production of free radicals can result in oxidative stress, causing imbalance and leading to oxidative damage, cell death, tissue damage and finally disease. Inhalation of cigarette smoke and exposure to air pollution contribute a lot to the generation of free radicals.

The intake of squalene as a health care supplement is crucial to deal with the pollution as the levels of squalene gets decreased due to pollution. Squalene can help a lot to deal with pollution by neutralizing the increased production of free radicals. Thus a number of medical conditions in children can be prevented by using squalene as a health supplement, which can occur due to increased free radicals.

Protects Against Infections2021-09-24T12:59:11+05:30

Infection is the invasion and multiplication of microbes as viruses, bacteria and parasites which are not usually present in the body. An infection can remain localized, or it can spread throughout the body through lymphatic vessels or the blood.

Children develop infections more frequently as compared to adults due to number of causes. It is found that the young children in child care centers are more susceptible to have infections as they have not developed the required protective immunities. Moreover, many children at pre-school age have not yet learned to properly wash their hands and thus germs from the hands of an infected child may get transmitted to others through sharing of toys or touching each other.

Well, it is the matter of concern if your child suffers from infections frequently as some diseases or medicines weaken the immune system. Therefore, if medicines lower the immune system, then it is better to choose an alternative treatment as health supplements. There are certain health supplements that can be considered for protecting your child against infections.

Squalene is known to be excellent health supplement for protecting against infections due to a number of benefits. Squalene has numerous health benefits. Protection against flu and infections is one of those benefits. Squalene has certain elements which improve the immunity of a person. According to the American Cancer Society, Squalene contains alkylglycerols that can defend against colds, viruses and other infections.

Alkylglycerols stimulate the immune system and give protection against uncontrolled, malignant cell growth. According to Swedish biochemist Sven Brohult, alkylglycerols aid the production of white corpuscles that are responsible for the optimal functioning of immune system. Alkylglycerols are also present in the body organs that are essential for immune defense as lymph nodes, spleen as well as in bone marrow and milk of the mother. Shark liver oil contains much more of it. Moreover, the macrophages present in Squalene have the ability to aid the healing of wounds.

Hence, the role of Squalene in protecting against infections and enhancing immunity is manifested.

Immunity Enhancer2021-09-24T12:58:19+05:30

It is normal for children to have infections caused by microorganisms such as bacteria, fungi or viruses. However, there reoccurrence is not normal. Reoccurring infections are the indications that there is problem of immune system in your child.

A child will suffer from a number of infections and life-threatening conditions if he or she does not possess a well-developed and maintained the immune system. Therefore, developed functioning of the immune system is highly important.

Squalene oil contains elements that improve the immune system of the individual. According to world health organization, Squalene has been used in certain flu vaccines. Every dose of Chriron flu and FLUAD vaccines contained nearly 10 mg of Squalene. Squalene is associated to improve immune response when used in some vaccines. According to studies, the element responsible for immune boosting is alkylglycerols, which researchers have found to fight off colds, viruses and infections. Alkylglycerols are one of the components present in Squalene oil. They are found to fight cancer by killing tumour cells indirectly. They activate the immune system by:

  • promoting immune system cells known as macrophages that consume attacking germs and damaged cells
  • blocking inhibiting protein kinase C that acts as a key regulator of cell growth

Alkylglycerols also decrease the adverse effects of chemotherapy and radiation treatment due to their ability to protect cell membranes.

Experimental studies reveal that Squalene-supplemented diets result in an increased response of the immune system. Medical conditions, as arthritis, psoriasis and asthma may also be improved by Squalene supplements. The laboratory studies confirmed that the function of macrophages is enhanced by Squalene. Macrophages are the type of white blood cells which ingests bacteria and virus. Macrophages have a vital role in the functioning of the immune system of our body. They also have the ability to help wounds heal faster.

In one of the studies, researchers studied that the expecting mothers who suffer from the urinary tract infections as inflammation in the urinary tract or bladder infections have improvement in their condition with the intake of shark liver oil. Thus it is evident that growing problems with antibiotic resistance can be cleared up by using shark liver oil as an alternative solution.

Squalene contains isoprenoid structures which are known to attach cell membranes. It has significant detoxification and antioxidant capacity. Antioxidants neutralize free radicals that can result in oxidative stress. The oxidative stress can result in oxidative damage, cell death, tissue damage and disease.

Therefore, it shows that Squalene has great potential as an immune-support nutrient. Thus for the maintenance of good immune response, intake of Squalene is quite promising.

Prevention and Treatment of Certain Cancers2021-09-24T12:57:25+05:30

Cancer is the result of cells which grow uncontrollably and do not die. Normal cells in the body grow, divide and die in an orderly path. This type of programmed cell death is known as apoptosis. When this path is broken down, cancer begins to form. The cancer cells do not undergo programmatic death and instead, they continue to grow and divide. This results in a mass of abnormal cells which grows out of control.

According to the American Cancer Society, Cancer is the second commonest cause of death in the US and it accounts for around 1 of every 4 deaths. It is a major cause of death worldwide. Deaths from cancer worldwide are rising continuously and estimated to be 13.1 million deaths in 2030.

Cancer researchers observed that there is a correlation between a high amount of squalene in shark and the absence of cancer in this species. The mechanism behind the action of squalene in preventing cancer is its ability to decrease mutated ras oncogene activation. Ras oncogene is a family of genes that produce proteins linked to the cell signalling pathways which manage cell growth and cell death. Studies have shown that squalene acts as an anti-cancer agent by decreasing farnesyl pyrophosphate (FPP) levels in cells as the prenylation of FPP is needed for oncogene activation.

Moreover, squalene is an excellent free radicals scavenger; therefore, it protects cells and organs from auto-oxidative damages. Squalene has antioxidant properties; therefore, it neutralizes the free radicals. The increased generation of free radicals can result in oxidative stress that can produce imbalance leading to oxidative damage, cell death, tissue damage and ultimately a medical condition.

It is better to prevent the occurrence of such a lethal disease rather than opting for unreliable treatments once such a disease attacks. Squalene being a product of natural resource does not cause any side effect. Its daily intake as a health supplement can reduce the risk of developing various types of cancers.

Libido Booster2021-09-24T12:56:52+05:30

Loss of libido is a common problem which affects up to one in five men at some point in their life. It is usually associated with personal and professional stress. But, an unexpected loss of libido particularly when it occurs continuously can be the sign of an underlying personal, lifestyle or medical problem that can be distressing to both partners in a relationship.

Testosterone hormone is most closely linked with male sex drive. It is a hormone which is produced mainly in the testicles. Low levels of testosterone usually cause low libido. Many men with low testosterone opt for testosterone therapy to improve their libido. However, it has a number of side effects as:

  • Acne or oily skin
  • Stimulation of prostate tissue, with possibly some increased urination symptoms
  • Elevated risk of developing prostate abnormalities
  • Increased risk of blood clots
  • Worsening of sleep apnea
  • Decreased testicular size
  • Increased aggression and mood swings
  • increased risk of heart attack

According to a number of studies, testosterone therapy can elevate the risk of a heart attack. This is one of the most serious risks of testosterone therapy. Men under 65 years of age with pre-existing heart disease are at greater risk of having a heart attack soon after starting testosterone therapy.

Thus it is better to choose something of natural origin to enhance your libido so as to avoid any side effects. Squalene is such a substance that is known to enhance libido or sexual vitality without causing any side effects as it has a natural origin. Various researchers show that Squalene helps in the formation of adrenal hormones as well as sex hormones for males including testosterone, androgens, vitamin D and other sex hormones. Therefore intake of squalene improves sexual vitality.

Moreover, the cellular activities in the scrotum are high thus nutrients and oxygen are constantly required in large quantities. The oxygen-supplying action of squalene enhances cellular activity in these organs; therefore the sexual vitality increases as the oxygen-rich cells ensure an efficient working of the body.

Hence it is evident that the use of squalene can help you to enhance your libido without suffering from any side effects as the other treatments for libido enhancement can cause.

Anti-Ageing Agent2021-09-24T12:55:50+05:30

Nobody can change the natural aging process. With time, it’s natural to get visible lines and lose youthful fullness on face. However, premature ageing signs are never pleasing for anyone, not even for men. There are number of causes behind the early ageing in men. However, sun damage, unhealthy lifestyle and medical conditions are the common ones.

Fortunately, men can prevent the risk of early ageing by using squalene as a health supplement. Squalene is found to be an excellent anti-aging substance due to its number of effects. It has a number of properties that are beneficial in keeping skin healthy and young. It helps a person to deal with pollution, ultraviolet rays and various health conditions that can cause premature aging. Its antioxidants properties play a vital role in performing all such functions. It is stable to attack free radicals. Increased formation of free radicals results in oxidative stress that causes imbalance and leads to oxidative damage, cell death, tissue damage and disease. Squalene reduces the oxidative stress and protects the skin against lipid peroxidation as a free oxygen scavenger.

There are some of the major benefits of squalene that makes it a best anti-ageing substance:

  • Squalene regenerates skin growth thus the skin remains healthy and smooth free from wrinkles and age spots.
  • Squalene interrupts free radicals and inhibits them from entering the body by protecting skin from environmental triggers that cause premature ageing.
  • Squalene enhances the moisture balance and elasticity to maintain the youngness of skin.
  • Squalene keeps you away from the conditions like acne, allergies, eczema, scars and psoriasis, which can contribute to premature ageing.
  • Squalene promotes improved blood circulation which helps to rejuvenate skin tone.
  • Squalene prevents the condition of obesity by acting as a fat regulator and reducing cholesterol levels. Thus by preventing obesity, it delays ageing because according to a study obesity accelerates the ageing process more than smoking.
  • Squalene acts as a stress buster thus it prevents premature ageing as stress is one of the major causes of early ageing.

Thus, the people who use squalene supplements are able to keep their skin young and flawless without any fine lines or wrinkles.

Increased stamina and energy2021-09-24T12:54:56+05:30

For every man, from factory workers to athletes, stamina is very important. Stamina means the capacity to carry on prolonged physical or mental effort. Well, the men who have strong immunity possess well-built stamina as the major function of the immune system is to protect our body from the microbes or chemicals. Otherwise, persistent infections and diseases can lead to the low energy level in the body and hence poor stamina. Therefore, developed functioning of the immune system is highly important to attain improved stamina.

Squalene oil contains elements that improve the immune system of the individual. According to studies, the element responsible for immune boosting is alkylglycerols, which researchers have found to fight off colds, viruses and infections. Alkylglycerols are one of the components present in squalene oil. They are found to fight cancer by killing tumour cells indirectly. They activate the immune system by:

  • promoting immune system cells known as macrophages that consume attacking germs and damaged cells
  • blocking inhibiting protein kinase C that acts as a key regulator of cell growth

Experimental studies reveal that squalene-supplemented diets result in an increased response of the immune system. Medical conditions, as arthritis, psoriasis and asthma may also be improved by squalene supplements. The laboratory studies confirmed that the function of macrophages is enhanced by squalene. Macrophages are the type of white blood cells which ingests bacteria and virus. Macrophages have a vital role in the functioning of the immune system of our body. They also have the ability to help wounds heal faster.

In one of the studies, researchers studied that the expecting mothers who suffer from the urinary tract infections as inflammation in the urinary tract or bladder infections have improvement in their condition with the intake of shark liver oil. Thus it is evident that growing problems with antibiotic resistance can be cleared up by using shark liver oil as an alternative solution.

Squalene contains isoprenoid structures which are known to attach cell membranes. It has significant detoxification and antioxidant capacity. Antioxidants neutralize free radicals that can result in oxidative stress. The oxidative stress can result in oxidative damage, cell death, tissue damage and disease.

Therefore, it shows that squalene has great potential as an immune-support nutrient. Thus, to attain good stamina intake of squalene is quite promising.

Controls the Condition of The Varicose Vein2021-09-24T12:53:57+05:30

Varicose vein is the condition, in which the veins become enlarged, gnarled and overfilled with blood. Varicose veins have bluish-purple or red colour and they appear as swollen and raised. They are usually painful. Any vein can become varicose, however, the veins of legs and feet most commonly get affected because standing and walking upright elevates the pressure in the veins of the lower body.

The risk of varicose vein is higher in aged people, females, obese people and who carry the family history of varicose vein. Moreover standing or sitting for long periods of time can also increase the risk of varicose vein.

Many studies have found that the women are more prone to develop varicose veins than men. It may be due to the hormone progesterone, which is produced by both men and women, but levels are much higher in women. Therefore, scientists believe that the progesterone is at least one of the reasons behind the susceptibility of women to develop varicose vein more. Along with regulation of menstrual cycles and the maintenance of many organs, the progesterone hormone also causes the relaxation of blood vessel wall. Researchers believe that, with the relaxation of these walls, the tiny valves present within the vessels also relaxes and the pressure exerted by flow of blood pushes out on the sides of the vessels. This makes them weaker and increases the risk of varicose veins.

There are various treatments available for varicose vein including self-care measures. However, the best option for controlling varicose vein is the use of squalene health supplements.

Role of Squalene in Controlling the Condition of Varicose Veins

The squalene controls the varicose veins in a number of ways:

  • By Improving Blood Circulation: Squalene improves the blood circulation by reducing the cholesterol in the body as it increases the high-level lipoproteins and decreases the low-level lipoproteins. Thus the levels of cholesterol in body decreases and arteries regain their size which facilitates improved blood circulation.
  • By Acting as Anti-Ageing: Squalene delays ageing in a number of ways as by preventing obesity, acting as anti-oxidant and stress buster thus it controls the condition of varicose veins. Therefore, the arteries remain elastic and the blood circulation remains continuous without any backflow.
Prevent the Occurrence of Certain Cancers2021-09-24T12:53:28+05:30

Breast cancer is a cancer, which forms in the cells of the breasts. Breast cancer is the second most common cancer diagnosed in women. Breast cancer can develop in both men and women; however, it is much more common in women. Some of the common symptoms of breast cancer can be breast lump, change in size of the breast, peeling, scaling or crusting of the pigmented area of skin around the nipple, changes in skin over the breast, redness or pitting of the skin over the breast.

Considerable support for breast cancer awareness has helped to create advances in its diagnosis and treatment. The survival rates have increased for breast cancer and the number of deaths linked with this disease is progressively declining because of the factors as detection at an early stage, a better understanding of the diseases and a new modified approach to treatment. Also, the studies were done by the researchers to show the benefits of squalene for breast cancer also helped the people to prevent the development of breast cancer.

Squalene is an excellent scavenger of free radicals; thus it protects cells and organs from auto-oxidative damages. On the other side, most antioxidants have side effects and they fail to get approval from certifying agencies. Hence, it is crucial to use antioxidants which are having essential characteristics as better safety profile and good oral availability. Squalene is among those antioxidants that match these characteristics.

Animal studies done in recent times shown that squalene in sebum play a protective role against the production of hydrocarbon carcinogens in the skin and also prevented the damages caused by radiation therapy. As it is a natural product, its consumption has no side effects, it is harmless. Several experimental studies have shown that the squalene is an excellent detoxifying agent against toxic and carcinogenic chemicals like hexachlorobiphenyl, theophylline, Phenobarbital, hexachlorobenzene, arsenic and strychnine.

It was found that those women who consume large quantities of olive oil have a much lesser risk of developing breast cancer. Therefore squalene is now being used in cancer patients as a prophylactic agent after irradiation treatment. The mechanism behind the function of squalene as prophylactics agent for cancer is its ability to reduce mutated ras oncogene activation. Ras oncogene is a family of genes which make proteins associated with cell signalling pathways that manage cell growth and cell death.

Thus it is evident that the consumption of squalene supplements can help to prevent the occurrence of breast cancer.

Superior Antioxidant2021-09-24T12:52:32+05:30

Oxygen is the great forgotten nutrient. Its deficiency is found to be the cause of nearly all degenerative diseases. Another threat to our cells is free radical, which causes diseases such as cancer, atherosclerosis, arthritis and diabetes. Free radicals are unstable molecules with unpaired electrons. Free radicals are produced constantly inside and outside the cell, and as by-products of energy-releasing oxidation in the mitochondria, others by UV light, radioactivity and the metabolism of drugs and chemicals.

Antioxidants neutralize these free radicals, otherwise increased generation of free radicals can result in oxidative stress, causing imbalance that leads to oxidative damage, cell death, tissue damage and disease.

Some of the benefits of antioxidants for human health are as follows:

  • Retards the signs of ageing
  • Healthier and young looking skin
  • Decreases the risk of cancer
  • Supports the detoxification
  • Longer life span
  • Protects against stroke and heart disease
  • Reduces the risk for cognitive problems
  • Decreases the risk of vision loss or eye disorders

Squalene is an excellent antioxidant due to its molecular structure. It possesses great capacity to receive or donate electrons without suffering molecular disruption. Squalene’s powerful free radical-quenching ability has been shown to be equal to that of BHT (butylated hydroxytoluene), one of the most powerful antioxidants known to science. This unique stability is the key to Squalene′s ability to terminate the on-going or chain damage inside our bodies (lipid peroxidation chain reaction). According to laboratory research, this happens specifically in the skin’s surface. It is reasonable to assume that it performs a similar function wherever it is found, for example within individual cells and in the biomembrane.

An Excellent Moisturizer & Skin Protector2021-09-24T12:51:40+05:30

Dry skin is a common condition which we all suffer at sometimes may be due to weather or any other reasons as poor diet. Dry skin looks rough and flaky and the risk of wrinkles for dry skin is quite high. Dry skin can result in a damaged barrier function, increasing long-term inflammation and sensitivity. It finally causes biochemical reactions as collagen breakdown. It can be very unpleasant especially for the women, as all women love to have smooth and supple skin.

Therefore it is very important for women to keep their skin moisturized to avoid early ageing and wrinkles by using moisturizing agents. There are a number of substances which are helpful in moisturizing the skin but the most beneficial for your skin is Squalene because it natural and does not carry any side effects along with it.

Squalene is naturally found in skin. Nearly 10% of the skin surface is formed of squalene. It helps to keep skin healthy in many ways. Moisture maintenance is among the major functions of squalene for skin health. It provides a protective layer to the skin which prevents loss of moisture. According to a research, squalene consumption gives protection to the skin. It also keeps skin healthy and prevents wrinkles. The unsaturated fatty acids present in squalene control the moisture of the skin. The skin which is moisturized never suffers dryness, dullness; flaking, scaling, peeling, cracking, and sagging and bagging that can cause premature ageing. Thus, squalene intake can help to keep skin moisturized and supple even in old age.

Remarkable Anti-Ageing Agent2021-09-24T12:51:13+05:30

Ageing is the natural process of becoming older. However premature aging takes place due to various reasons as poor diet, stress, lack of exercise or lack of enough sleep. Several other factors as high pollution, sun, and ultraviolet exposure also play an important role in causing premature aging. Signs of aging can be classified into four main categories:

  • wrinkles
  • pigmentation heterogeneities
  • lack of firmness of cutaneous tissues
  • vascular disorders

All these aging signs are distressing especially for women when they appear. They may lose their confidence and feel uncomfortable in society due to their looks. Well, it is hard to control natural aging but we can prevent premature aging caused by exposure to ultraviolet rays, excess pollution, and sun. This can be done by following several preventive measures and using health supplements that can help you to stay young and keep your skin free from signs of aging. Among a number of a preventive measure against aging, use of health supplements is the excellent and easiest one. Nowadays, many health supplements are accessible that can act as anti-aging. Well, one should have to choose the best among them.

Squalene is found to be an excellent anti-aging substance due to its number of effects. It has a number of properties that are beneficial in keeping skin healthy and young. It helps a person to deal with pollution, ultraviolet rays and various health conditions that can cause premature aging. Its antioxidants properties play a vital role in performing all such functions. It is an excellent antioxidant that has no side effects. It is stable to attack free radicals. Increased formation of free radicals results in oxidative stress that causes imbalance and leads to oxidative damage, cell death, tissue damage and disease. Squalene reduces the oxidative stress and protects the skin against lipid peroxidation as a free oxygen scavenger.

Thus we can conclude that use of squalene in our daily life can help us to keep our skin young naturally. Moreover, with the use of squalene, you need not fear about any side effects as it is natural substance. For women, squalene can act as a miracle in keeping their skin without any flaws and aging signs.

Weight Management2021-09-24T11:31:59+05:30

Omega-3 fatty acids may facilitate weight loss. They do so by

  • Modulating metabolism of fats by stimulating lipolysis or breakdown of stored fat.
  • Increasing production of leptin, an appetite-controlling hormone that also has an important fat-burning role.
  • Decreasing lipogenic enzymes that check storage of fat in the body.

By helping regulate blood sugar levels in the body, a diet rich in omega-3 fatty acids can help keep hunger in check, thus aiding weight loss. In overweight and obese volunteers, there were fewer hunger sensations in the omega-3 fatty acid group immediately after the test dinner and after 120 minutes. Combining fish-oil supplements with regular aerobic exercise improves body composition by reducing body fat. In a study, 66% of young European overweight adults consumed less than the generally the recommended intake of fish.


Osteoporosis is a disease in which the bones become weak and are more prone to fractures. It is also called as the ‘silent disease’ as bone is lost with no signs. Such fractures are common in the hip, spine and wrist. Osteoporosis can strike at any age but is most common in older women.

An expanding body of evidence indicates that omega-3 fatty acids are also beneficial to bone health. They may help increase calcium levels in the body, deposit calcium in the bones and enhance bone strength. Studies have also indicated that individuals who lack essential fatty acids (particularly EPA and gamma-linolenic acid [GLA], an omega-6 fatty acid) are more prone to develop loss of bone than those with adequate levels of these EFAs.

In a study of elderly women with osteoporosis, those who were given EPA and GLA supplements had considerably less bone loss over a period of three years than those who were given a placebo. Many of these women also experienced an increase in bone density during this time. In young healthy men, an 8-year study showed that omega-3 fatty acids, especially DHA was positively associated with an increase in bone mineral and, hence, with peak bone mineral density (BMD). The study by Weiss et al has observed a negative association between a higher omega-6 to omega-3 fatty acids ratio and bone density at the hip in both sexes.

Mental Health2021-09-24T11:30:31+05:30

The brain is one of the organs in the body with the highest level of lipids (fats). Omega-3 fatty acids are important components of nerve cell membranes. DHA, in particular, is involved in various nerve cell processes. Omega-3 fatty acids from fatty fish in the human diet may be effective in the prevention of stress and other disease conditions including depression, and dementia.


In a review of evidence of omega-3 fatty acid in depression, four of seven trials showed significant improvement of depression with at least 1 g/day of EPA. Results from a trial have also shown therapeutic benefits with omega-3 fatty acids in depression during pregnancy. In a Finnish study, the risk of depression and suicidality was much lower in those who frequently ate fish.

Bipolar Disorder

Scientists in Taiwan compared omega-3 supplementation (10 capsules per day, each containing EPA 440 mg and DHA 220 mg) with usual treatment in patients diagnosed with a major depressive disorder for a duration of eight weeks and concluded that omega-3 PUFAs could improve the short-term course of illness. Patients on omega-3 supplementation experienced a significantly greater decrease in the Hamilton Depression Scale score than did those in the control group. In another clinical study of 30 people with bipolar disorder, omega-3 fatty acids (EPA and DHA 9.6 g/day) in addition to usual treatment for four months could maintain mood stability; also, patients experienced fewer mood swings and recurrence of either depression or mania than those who received a controlled drug.


Preliminary clinical evidence suggests that people with schizophrenia experience an improvement in symptoms when given omega-3 fatty acids. Omega-3 fatty acids reduce the antipsychotic drug requirement in first episode patients with schizophrenia and may be an effective adjunct to antipsychotics. But, a recent study observed no additional benefits of EPA supplements than placebo in improving symptoms of schizophrenia.

Attention Deficit/Hyperactivity Disorder

Children with attention-deficit/hyperactivity disorder (ADHD) may have low levels of EFAs including EPA and DHA. In a clinical study of about 100 boys, learning and behavioral problems (such as temper tantrums and sleep disturbances) were more common in boys with lower omega-3 fatty acid levels than those with normal omega-3 fatty acid levels.


A child diagnosed with autism who received 540 mg of the omega-3 fatty acid daily in the form of EPA for four weeks experienced a complete end to his previous anxiety about everyday events as reported by his parents and clinician. His overall quality-of-life was also improved. In another trial, most parents of 18 children with autism who had been given fish oil supplements for six months described improvements in overall health, cognition, sleep patterns, social interactions and eye contact. A recent trial reported reduced hyperactivity and reduced stereotypy (repeated movements like hand-flapping) in children who received 1.5 g of fish oil per day, as compared to children who received placebo.

Eating Disorders

Omega-3 fatty acids have also been researched in eating disorders such as anorexia nervosa. In a pilot study of EPA supplementation in the treatment of anorexia nervosa in seven young patients, three recovered and four improved.


Omega-3 fatty acid supplementation may have an inverse relationship with the risk of dementia and cognitive decline. People who have diets rich in fish would have a significantly lower risk of dementia and Alzheimer’s disease. Omega-3 fatty acid supplements may slow cognitive decline in some patients with very mild Alzheimer’s disease, though they do not appear to affect those with more advanced cases. A study by researchers at Tufts University in Boston found that people with the highest blood levels of DHA had a 47% lower risk of developing dementia and a 39% lower risk of developing Alzheimer’s. The study analyzed the blood of 899 men and women with an average age of 76. All participants were free of dementia at the beginning of the study, and underwent neuropsychological testing after giving their initial blood sample. In patients with mild cognitive impairment, a significant improvement in the cognitive portion of the Alzheimer’s Disease Assessment Scale (ADAS-cog) was noted.

Menstrual Pain2021-09-24T11:29:11+05:30

Menstrual pain or dysmenorrhea is the most common gynecologic complaint and the leading cause of short-term absenteeism among adolescent schoolgirls. In a clinical study of nearly 200 Danish women aged between 20 and 45 years, a strong association was observed between increased menstrual pain and a low intake of omega-3 fatty acids from fish.

In a study, adolescents suffered less menstrual pain while taking fish oil supplementation; the amount of painkillers taken during the menstrual periods also declined by more than 50%.


Omega-3 fatty acids relieve depressive symptoms related to menopause. A study published in the American Journal of Clinical Nutrition presented the first evidence that EPA supplementation is effective for treating common menopause-related mental health problems and improves depressive symptoms. Middle-aged women were grouped into two and were randomly administered either daily supplements of omega-3 fatty acids (EPA+DHA) or placebo (sunflower oil) for eight weeks. At the beginning of the study, all of the participants were classified as having mild-to-moderate depression and about one-quarter of them had experienced major depressive episode. Omega-3 fatty acids significantly improved the condition of women suffering symptoms of psychological distress and mild depression at the end of the study. The researchers also noted that the difference in the observed results between the two groups was remarkable especially keeping in view that omega-3 fatty acids have very few side effects and are beneficial to heart health.

Omega-3 Fatty Acids Improve Hot Flashes

Supplementation with EPA omega-3 fatty acids reduced frequency of hot flashes (HF) and also improved the HF score relative to placebo. At the start of the study, the number of daily hot flashes experienced by the women was 2.8 in a day. There was a significant decrease in the number of daily hot flashes over the 8-week study, with a greater decrease observed among women consuming EPA. The number of hot flashes declined by 1.58/day in the EPA group versus 0.5/day decrease in the control group. The quality-of-life also improved in both groups.59

Inflammatory Bowel Disease2021-09-24T11:26:31+05:30

The term ‘inflammatory bowel disease (IBD) refers to two chronic diseases that cause inflammation of the bowels or intestines: ulcerative colitis and Crohn’s disease. Omega-3 fatty acids have the most potent immunomodulatory activities, and among the omega-3 PUFA, those from fish oil (EPA and DHA) are more biologically potent than ALA. Hence, these fatty acids may inhibit an increase of proinflammatory markers. When added to standard medication, such as sulfasalazine, omega-3 fatty acids may reduce symptoms of Crohn’s disease and ulcerative colitis. In children with Crohn’s disease, omega-3 FAs (EPA and DHA) together with mesalazine treatment (5-ASA) effectively maintained disease remission. Children who were given omega-3 fatty acids also suffered fewer relapses.


Earlier studies have reported a lower prevalence of impaired glucose tolerance and type 2 diabetes in populations who took large amounts of omega-3 fatty acids found mainly in fish. People with type 2 diabetes are known to be at increased risk of heart attack or stroke. Diabetics typically have high levels of fats (TGs) in the blood, low levels of good cholesterol (HDL cholesterol) and abnormal LDL (low-density lipoprotein) composition. Omega-3 fatty acids from fish lower TGs, reduce abnormal heart rhythms, lower blood pressure and improve blood clotting regulation. Clinical studies have shown that consumption of omega-3 fatty acids has cardioprotective effects in persons with type 2 diabetes without adverse effects on glucose control and insulin activity.

Fish oil may be useful in treating dyslipidemia in diabetes. Fish oil supplementation improved plasma VLDL cholesterol, VLDL TGs, and total TGs while having a transient deterioration in LDL cholesterol in patients with noninsulin-dependent diabetes (NIDDM). Furthermore, fish oil supplementation had no significant deleterious effect on glycemic control. Plasma LDL cholesterol was temporarily increased in the fish oil group at 6 weeks, but the effect was no longer present at 12 weeks. A diet rich in fish and other sources of omega-3 fatty acids reduces the chances of children with a family history of diabetes to develop the disease. In type 2 diabetic patients, supplementation with 1.7 g/day to all patients for a further six months produced no deterioration of glucose control after one year of treatment. Preliminary evidence suggests increased consumption of n-3 PUFAs with reduced intake of saturated fat may reduce the risk of conversion from impaired glucose tolerance to type 2 diabetes in overweight persons.

Bronchial Asthma2021-09-24T11:13:56+05:30

Asthma has been defined as a chronic inflammatory disease of the airways. Due to their anti-inflammatory properties, research suggests that omega-3 fatty acid supplements may decrease inflammation and improve lung function in patients with asthma. One clinical trial of omega-3 fatty acids supplementation in children with asthma found that those who took fish oil supplements rich in EPA and DHA for 10 months had improvement in their symptoms compared to children who took a placebo pill.

An Australian study showed that eating oily fish more than once per week protects children against asthma. Omega-3 fatty acids are also useful in reducing exercise-induced asthma.


Taking a diet rich in omega-3 fatty acids is beneficial to patients with arthritis such as rheumatoid arthritis and osteoarthritis as they slow down the development of the joint disease. Fish oil supplementation is, therefore, a valuable support to the conventional drug treatment of rheumatoid arthritis. Studies have shown that patients taking fish oil supplements for rheumatoid arthritis require fewer pain medications. In a recent study, a significant reduction in the patient-reported intensity of joint, duration of morning stiffness, number of painful and/or tender joints including consumption of painkillers (NSAIDs) has been reported with omega-3 fatty acids.

Omega-3 Fatty Acids Regress Blockages2021-09-24T11:08:42+05:30

Omega-3 fatty acids have antiatherosclerotic effect i.e. fish oil consumption may modestly reduce chronic progression of atherosclerosis, commonly referred to as a ‘hardening’ of the blood vessels (arteries). A clinical trial observed modest but statistically significant effects of fish oil supplementation on progression of coronary, but not carotid, atherosclerosis. Patients with CAD who took about 1.5 g of omega-3 fatty acids per day for two years had less progression and more regression of CAD on coronary angiography than did comparable patients who ingested a placebo. These patients also experienced fewer cardiovascular events. Another trial examined the effects of EPA (1.8 g/day for 2.1 years) on the progression of carotid atherosclerosis in 81 Japanese patients with type 2 diabetes. Individuals who were given EPA had less progression of both mean and maximal intimal medial thickness.

Omega-3 Fatty Acids Prevent Heart Disease2021-09-24T11:07:18+05:30

People who eat more fish generally have a lower risk of CAD and death due to heart disease. A large clinical trial, JELIS, examined the effects of EPA on CAD in patients with high cholesterol levels. Some of these patients on statin drugs (to control cholesterol levels in the blood) but with no evidence of CAD were administered EPA, while others were not. The scientists investigated relationships between the occurrence of CAD, the number of CAD risk factors (obesity, hypercholesterolemia, high TG or low HDL-C, diabetes and hypertension) and EPA treatment. In the higher risk group (TG ≥150 mg/dl; HDL-C < 40 mg/dl), EPA treatment prevented the risk of CAD by 53%. In a meta-analysis of studies of 222,364 individuals, the risk of death due to CHD gradually declined in individuals who ate fish one to three times per month, once per week, two to four times per week, or more than four times per week than in those who ate fish less than once per month. The GISSI-Prevenzione Trial showed that the beneficial effects of fish consumption are related to intake of n-3 fatty acids, which have been shown in trials of supplements to decrease subsequent cardiovascular disease.

Omega-3 Fatty Acids Normalize Heart Rhythm and Lower Chances of Sudden Death2021-09-24T11:06:23+05:30

Death from coronary heart disease (CHD) (heart attack and chest pain) can be due to heart failure, arrhythmias (abnormally fast or slow heart rhythm) or sudden cardiac death (SCD). Most SCD is due to ventricular fibrillation (abnormal irregular rhythm of the heart where the ventricles i.e. lower chambers of the heart, contract in a very rapid, unsynchronized manner ′fluttering′). The risk of death and sudden death is highest in the first months following a heart attack.

One of the most remarkable benefits of fish oils is their ability to prevent sudden death, SCD in particular. They have antiarrhythmic effect i.e. reducing potentially fatal abnormal heart rhythms, or arrhythmias that lead to SCD and thus offer protection against cardiac sudden death. Fish oil is particularly effective in fighting the common but worrying heart arrhythmia known as atrial fibrillation abnormal heart rhythm that involves the two upper chambers or the atria of the heart. This is especially important, as atrial fibrillation increases the risk of stroke.

More than 2,000 men with previous heart attack were studied to examine the life-saving beneficial action of fish oil. Some were advised to regularly eat fish, while others were not asked to do so. The difference in mortality observed between the two groups after two years was dramatic. Men who consumed fish oil twice a week had a 29% lower rate of death than those who did not. According to the researchers, fish oil helped prevent death in these men with a history of heart muscle damage by stopping the abnormal heart rhythms. Another important study showed that regular consumption of fish is associated with a decrease in heart rate in healthy men. In a study, 9,758 men from Lille (France) and Belfast (Ireland) aged 50-59 years with no previous CHD were grouped according to the amount of fish they consumed on a normal basis.

  • 27% ate fish less than once per week
  • 47% ate fish once per week
  • 20% had fish twice per week
  • 6% ate fish more than twice per week

Regular consumption of fish is associated with decreased heart rate in healthy men which lower the chances of sudden death among fish eaters. In men who ate fish less than once per week, the average heartbeat was 67.5 beats/minute, whereas, the average heartbeat was 65.6 beats/minute in men who ate fish more than twice per week. In a small group of patients undergoing cardiac surgery, consumption of fish oil (2 g/day) for at least five days before elective CABG and until the day of discharge from the hospital markedly reduced the incidence of post-operative AF (54.4%) and was associated with a shorter hospital stay. Another study also found an association between fish oil consumption and reduced risk of atrial fibrillation. It has been shown that patients who develop arrhythmias often have low omega-3 fatty acid levels in their blood. This further affirms the usefulness of omega-3 fatty acids supplementation in promoting healthy heart rhythm.

In a group of 84,688 women aged 34-59 years, from the US Nurses′ Health Study, higher consumption of fish and n-3 fatty acids caused fewer deaths. Compared with fish consumption intake of less than once a month, eating fish at least five times a week lessened the risk of overall death by 32%. Compared with the lowest quintile of omega-3 fatty acid intake, the highest quintile was associated with a 25% reduced risk of overall death. The results also suggested that fish consumption is more protective against fatal CHD than nonfatal myocardial infarction. Oily fish consumption was associated with a 34% reduced risk of death due to CHD during 20 years of follow-up compared with no oily fish consumption. Consumption of 15 g/day of lean fish is equal to about 50 mg of omega-3 fatty acids; in contrast, 15 g/day of oily fish provides about 400 mg of omega-3 fatty acids.

The Time-course of Any Benefit Appears Early

In a major clinical study, the GISSI-Prevenzione trial, in patients with recent heart attack, fish oil reduced mortality, entirely due to fewer SCDs. The protective benefits of fish oil were evident after only a few months of supplementation. In this large study of more than 11,000 adults, those who consumed 1,000 mg of EPA and DHA daily (taken as fish oil supplement) had a 42% reduction in SCDs within the three-month period following a heart attack compared to patients who received no omega-3 fatty acids. These life-saving benefits persisted beyond the initial 3-month danger period as evident by a death rate of 8.4% among the participants who had received the fish oil supplement and 9.8% among those who had not received the fish oil supplement by the end of the 42-month follow-up period.

Omega-3 Fatty Acids Lower Blood Pressure2021-09-24T11:05:00+05:30

In older persons and those with high BP (or hypertension), fish oil supplementation considerably decreased both systolic (upper reading of BP) and diastolic BP (lower reading of BP). A study has shown a greater fall in both systolic and diastolic BP in men with high BP at risk of heart disease, with fish oil consumption. The men included in the study were assigned to five high-fat (40% of daily energy) and two low-fat (30% of energy) groups. The five high-fat groups were assigned to take either six or 12 fish-oil capsules daily, fish or a combination of fish oil and fish, or placebo capsules. The two low-fat groups took either fish or placebo capsules. Omega-3 fatty acids from fish oils improve BP control and may reduce the long-term continuous rise in BP in patients who had hypertension and who underwent a heart transplant. The study also illustrated a favorable effect of omega-3 fatty acids on kidney function in these patients.

Omega-3 Fatty Acids Increase Good Cholesterol and Lower Triglycerides2021-09-24T11:04:21+05:30

Impact of High Triglyceride Levels

Hypertriglyceridemia or high levels of triglycerides (TGs) in blood greatly increase the risk for heart disease.

  • High TG levels are a causative factor for small, dense LDL (cholesterol in low-density lipoproteins or the ′bad′ cholesterol) particles that are more atherogenic than larger LDL particles.
  • High TG levels reduce levels of HDL or ′good′ cholesterol.
  • High TG levels may unfavourably affect the coagulation system and increase the danger of thrombosis (clot formation). An increase in the risk of thrombosis increases the risk of cardiac events.

Omega-3 Fatty Acids and High Triglyceride Levels

Omega-3 fatty acids in fish oils markedly decrease TGs and very low-density lipoprotein (VLDL) levels in blood and help correct other risk factors for heart disease. The hypotriglyceridemic effect of fish oil appears to be caused mainly by blocking the production of VLDL-triglyceride, but an additional, independent effect upon the breakdown of VLDL molecules into simpler ones cannot be ruled out. They also increase HDL cholesterol. A unique effect of omega-3 fatty acids is to hasten the clearance of fat-containing particles from the blood following meals. This remarkable fat-clearing ability has important implications for prevention of heart disease. According to scientists, this rise in blood fat levels following a meal, known as postprandial hyperlipidemia, may be a potent contributor to atherosclerosis and thus to a heart attack.

Omega-3 fatty acids are required in higher doses to reduce elevated TG levels (2-4 g/day). A unique effect of omega-3 fatty acids is to hasten the clearance of fat-containing particles from the blood following meals. This remarkable fat-clearing ability has important implications for prevention of heart disease.

Fish oil supplementation raises HDL cholesterol (HDL-C) concentrations (+3%) and, particularly in patients with hypertriglyceridemia. They also lower the proportion of small dense LDL-C particles. The rise in LDL cholesterol of up to 5% seen with fish oil consumption is due to increase in LDL particle size i.e. LDL-C concentration may slightly increase but without appreciable change in the number of circulating LDL particles. In persons with hypertriglyceridemia that is resistant to treatment, fish oil supplements (more than 3 g/day of DHA and EPA) can lower the serum TGs by as much as 50% or more.

Omega-3 Fatty Acids in Acute Coronary Syndrome2021-09-24T11:03:25+05:30

The term ‘acute coronary syndrome’ comprises a range of coronary artery diseases (CADs), including unstable angina, ST-elevation myocardial infarction (STEMI; often termed as “Q-wave myocardial infarction”), and non-STEMI (NSTEMI; often referred to as “non-Q-wave myocardial infarction”). Symptoms of the acute coronary syndrome include chest pain, referred pain, nausea, vomiting, breathlessness (or dyspnea), sweating (or diaphoresis) and lightheadedness. Consumption of high levels of fish oil (more than 1 g/day) for a long time may reduce the risk of nonfatal heart attacks and acute coronary syndrome.

Omega-3 Fatty Acids and Heart Failure2021-09-24T10:43:15+05:30

Omega-3 fatty acids have the ability to lower the risk of heart failure. One major cause of CHF is myocardial infarction or heart attack which is an irreversible injury to heart muscle. According to a clinical trial reported in the European Heart Journal, moderate intake of fatty fish and marine omega-3 fatty acids caused lower rates of heart failure. Men who ate fatty fish once a week had 12% less chances of developing heart failure compared to those who never ate fatty fish. Men who consumed approximately 0.36 g/day were 33% less likely to develop heart failure than men who consumed little or no marine omega-3 fatty acids (0.15-0.22 g/day). Higher intake offered no additional benefit. Consumption of baked or broiled fish is also associated with reduced risk of incident heart failure; consumption of fried fish was associated with an increased risk of heart failure.

What is Squalin?2021-09-23T08:30:41+05:30

What is Squalin (99% Pure Squalene)?

Permalife Squalin® is the excellent source of 99% pure Squalene, which is extracted from the deep sea sharks. Its prolonged use has been found safe as this natural compound is found in our bodies and also found in nature, mostly in plant sources including amaranth seed, olives, rice bran and wheat germ. It can be consumed at high levels through the diet alone, although supplementation can also help.

Healthy as well as imbalance of our body has its origin on the cellular level. The healthier our cells are, the healthier we are. The source of Squalin is essential substance from the very beginning of life. It can be explained by the presence of high concentration of Squalene in newborn babies, responsible for their soft skin, and such babies need to strengthen the immune system in no time after birth. The body of babies and pre-schoolers show the highest levels of Squalene. This fact explains the energetic behaviour and the vivid eyes of young and healthy children. Another fact is, starting with an age of 25 the Squalene level in our body drops significantly. Therefore it is not surprising that round an age of 30 the sports performances of most humans decline. Squalin being 99% pure Squalene can intercept this lack of energy and improve the power output and help protect us from several health ailments.

Squalin acts as a strong antioxidant that helps our cells to avoid oxidative stress and prevents lipid peroxidation. It acts as an immune booster and has the ability to protect cellular structures and improve cellular repair response. It has a crucial role in the moisture regulation of the skin and transportation of the oxygen to and from the skin. It also has positive effects in the management of dermatitis and skin cancer. It regulates the rate of synthesis of HMG Co-A reductase enzyme. It also shows anticancer and cholesterol-lowering benefits.


About Seatone

Aroma Seatone GLME® (Biolane Extract) is made from extract of Green Lipped Mussel (GLM), an edible shellfish found off the coast of New Zealand. Since its discovery in 1974, Seatone GLME has been subjected to more than forty years of quality scientific research and the joint health benefits have been shown in laboratory and clinical trials. It is found to be beneficial in both osteoarthritis and rheumatoid arthritis. It aids in the recovery of injuries or surgery to joints.

Seatone GLME contains anti-inflammatory agents, immune modulators and many essential building blocks – all naturally occurring substantial therapeutic agents known to maintain joint mobility & wellbeing.

It is known to provide relief from pain, protecting cartilage, repairing joints, reducing the inflammation and improving general mobility. It usually provides relief which may be gradual, progressive and normally long-term. The first thing to be noticed is a reduction in pain, which is then followed by gradual improvement in grip strength, freedom of movement or other mobility. Most people see visible improvement after 4-8 weeks of starting Seatone GLME, but it can take up to 3 months.

GLM is widely consumed by the local population of New Zealand and is classified as a ′basic food status′ product. No adverse effects have been reported with long-term use even at high levels of consumption. Toxicity studies at Auckland Hospital were unable to find toxic level of Seatone GLME at 120 times the standard dosage.

Seatone® is a trusted brand from more than 40 years and is sold in over 30 countries.


New Zealand Green Lipped Mussel Extract2021-09-23T08:49:04+05:30

New Zealand Green Lipped Mussel Extract

Green lipped mussel is a shellfish which is native of New Zealand. It gets it′s name due to the green lip surrounding the edge of its shell. They may grow up to 240 mm in length, making them one of the largest mussel species. They are grown in pristine coastal waters of New Zealand. To maintain the quality of mussels, seawater in the farms is tested for bacteria, Biotoxins and heavy metals. The water quality is tested out according to the standards set by the European Union, U.S Food and Drug Administration, and NZ Food Safety Authority.

It was found in 1974 that the green lipped mussel is a potential natural remedy for arthritis. Thus it is available commercially as a food supplement from 1974. It is found to be effective in the treatment of both rheumatoid arthritis and osteoarthritis after laboratory and clinical trials which were done on both human and animal subjects. It works by anti-inflammatory activities. It blocks the migration of neutrophils (soldier cells) from the blood vessels thus it inhibits them from attacking our own cells in conditions when an inflammatory spur is present. Thus it helps to reduce the pain and increases mobility. It owns a property of being gastro-protective thus it does not damage the soft lining of stomach and also protects the stomach lining from the harsh effects of the some of the pain killers that a person takes during the conditions of arthritis.

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